Organic Lab Report
Organic Lab Report
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Organic chem- esterification mechanism?
There are 2 questions in my lab report:
1. Write out mechanism for generic Fischer esterification without acid catalyst.
2. Write out mechanism for Fischer esterification with acid catalyst. Note the similarities b/t with and without acid catalyst.
I know what the mechanism for acid-catalyzed is, but I thought one of the requirements of Fischer esterification was that there be an acid catalyst. What does he mean by “generic” mechanism???
You are correct that a Fischer projection requires an acid catalyst. It is extremely slow without one.
One possible answer is to use a molecule of the carboxylic acid as the catalyst rather than an added acid catalyst.
Another is to add the alcohol to the C=O carbon and have a + on the alcohol O after the addition and a – on the former C=O oxygen. Move the extra H to the OH that came from the carboxylic acid then bring the electrons on the O- down and lose H2O.
Digital Lab Report
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